| Title |
Defining a multimodal signature of remote sports concussions
|
|---|---|
| Published in |
European Journal of Neuroscience, May 2017
|
| DOI | 10.1111/ejn.13583 |
| Pubmed ID | |
| Authors |
Sébastien Tremblay, Yasser Iturria‐Medina, José María Mateos‐Pérez, Alan C. Evans, Louis De Beaumont |
| Abstract |
Sports-related concussions lead to persistent anomalies of the brain structure and function that interact with the effects of normal ageing. Although post-mortem investigations have proposed a bio-signature of remote concussions, there is still no clear in vivo signature. In the current study, we characterized white matter integrity in retired athletes with a history of remote concussions by conducting a full-brain, diffusion-based connectivity analysis. Next, we combined MRI diffusion markers with MR spectroscopic, MRI volumetric, neurobehavioral and genetic markers to identify a multidimensional in vivo signature of remote concussions. Machine learning classifiers trained to detect remote concussions using this signature achieved detection accuracies up to 90% (sensitivity: 93%, specificity: 87%). These automated classifiers identified white matter integrity as the hallmark of remote concussions and could provide, following further validation, a preliminary unbiased detection tool to help medical and legal experts rule out concussion history in patients presenting or complaining about late-life abnormal cognitive decline. |
X Demographics
The data shown below were collected from the profiles of 22 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 14% |
| United Kingdom | 2 | 9% |
| Canada | 2 | 9% |
| Spain | 1 | 5% |
| Hungary | 1 | 5% |
| Switzerland | 1 | 5% |
| Kuwait | 1 | 5% |
| France | 1 | 5% |
| Unknown | 10 | 45% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 14 | 64% |
| Scientists | 4 | 18% |
| Science communicators (journalists, bloggers, editors) | 3 | 14% |
| Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 126 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 126 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 22 | 17% |
| Student > Master | 15 | 12% |
| Student > Ph. D. Student | 14 | 11% |
| Student > Doctoral Student | 10 | 8% |
| Researcher | 10 | 8% |
| Other | 19 | 15% |
| Unknown | 36 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 21% |
| Neuroscience | 14 | 11% |
| Psychology | 11 | 9% |
| Sports and Recreations | 7 | 6% |
| Nursing and Health Professions | 5 | 4% |
| Other | 22 | 17% |
| Unknown | 41 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 111. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2018.
All research outputs
#368,390
of 25,028,065 outputs
Outputs from European Journal of Neuroscience
#34
of 6,126 outputs
Outputs of similar age
#7,718
of 316,184 outputs
Outputs of similar age from European Journal of Neuroscience
#1
of 54 outputs
Altmetric has tracked 25,028,065 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,126 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,184 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.