| Title |
A synthetic stimulant never tested in humans, 1,3‐dimethylbutylamine (DMBA), is identified in multiple dietary supplements
|
|---|---|
| Published in |
Drug Testing and Analysis, October 2014
|
| DOI | 10.1002/dta.1735 |
| Pubmed ID | |
| Authors |
Pieter A. Cohen, John C. Travis, Bastiaan J. Venhuis |
| Abstract |
A synthetic stimulant never before studied in humans, 1,3-dimethylbutylamine (DMBA), was suspected of being present in dietary supplements. DMBA is an analogue of the pharmaceutical stimulant, 1,3-dimethylamylamine (DMAA), which was recently banned by the US Food and Drug Administration. We obtained all dietary supplements sold by US distributors that listed an ingredient on the label, such as AMP Citrate, that might be a marketing name for DMBA. Supplements were analyzed for the presence and quantity of DMBA. Fourteen supplements met our inclusion criteria and were analyzed by two separate laboratories using ultra high performance liquid chromatography (UHPLC) - mass spectrometry and a reference standard. The identity of DMBA was confirmed in 12 supplements in the range of 13 to 120 mg DMBA per serving. Following recommendations on the supplement label for maximum daily intake, customers would consume from 26 to 320 mg of DMBA per day. Supplements containing DMBA were marketed to improve athletic performance, increase weight loss and enhance brain function. DMBA has never before been detected in supplements. The stimulant has never been studied in humans; its efficacy and safety are entirely unknown. Regulatory agencies should act expeditiously to warn consumers and remove DMBA from all dietary supplements. Copyright © 2014 John Wiley & Sons, Ltd. |
X Demographics
The data shown below were collected from the profiles of 74 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 27 | 36% |
| United Kingdom | 6 | 8% |
| Australia | 2 | 3% |
| Canada | 2 | 3% |
| Portugal | 2 | 3% |
| Jamaica | 1 | 1% |
| Spain | 1 | 1% |
| Italy | 1 | 1% |
| Norway | 1 | 1% |
| Other | 1 | 1% |
| Unknown | 30 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 43 | 58% |
| Practitioners (doctors, other healthcare professionals) | 23 | 31% |
| Scientists | 8 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 2% |
| Unknown | 58 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 20% |
| Student > Bachelor | 8 | 14% |
| Student > Master | 7 | 12% |
| Other | 5 | 8% |
| Student > Ph. D. Student | 3 | 5% |
| Other | 10 | 17% |
| Unknown | 14 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 15 | 25% |
| Agricultural and Biological Sciences | 6 | 10% |
| Biochemistry, Genetics and Molecular Biology | 5 | 8% |
| Sports and Recreations | 4 | 7% |
| Medicine and Dentistry | 4 | 7% |
| Other | 10 | 17% |
| Unknown | 15 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 290. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2019.
All research outputs
#120,032
of 25,320,147 outputs
Outputs from Drug Testing and Analysis
#6
of 1,507 outputs
Outputs of similar age
#1,044
of 262,385 outputs
Outputs of similar age from Drug Testing and Analysis
#1
of 25 outputs
Altmetric has tracked 25,320,147 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,507 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.