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An amphetamine isomer whose efficacy and safety in humans has never been studied, β-methylphenylethylamine (BMPEA), is found in multiple dietary supplements

Overview of attention for article published in Drug Testing and Analysis, April 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#4 of 1,011)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
45 news outlets
blogs
17 blogs
twitter
71 tweeters
facebook
13 Facebook pages
wikipedia
3 Wikipedia pages
googleplus
3 Google+ users
reddit
3 Redditors

Citations

dimensions_citation
43 Dimensions

Readers on

mendeley
62 Mendeley
Title
An amphetamine isomer whose efficacy and safety in humans has never been studied, β-methylphenylethylamine (BMPEA), is found in multiple dietary supplements
Published in
Drug Testing and Analysis, April 2015
DOI 10.1002/dta.1793
Pubmed ID
Authors

Pieter A. Cohen, Clayton Bloszies, Caleb Yee, Roy Gerona

Abstract

The amphetamine isomer β-methylphenylethylamine (BMPEA) was first synthesized in the early 1930s, but its efficacy and safety in humans has not been studied. Recently, the United States Food and Drug Administration (FDA) detected BMPEA in dietary supplements labelled as containing Acacia rigidula. Over a year after the FDA reported its findings, we analyzed Acacia rigidula dietary supplements to determine if BMPEA had been removed. Supplements were analyzed using liquid chromatography-quadrupole time-of-flight mass spectrometry. Diluted methanolic extract from each supplement was run three times and each data set obtained was analyzed using Agilent MassHunter Qualitative Analysis. The presence of BMPEA was confirmed by accurate mass, retention time and mass spectra match against a reference standard. Quantification of BMPEA was determined using an eight-point calibration curve of spiked standard to a matrix blank. Twenty-one brands of Acacia rigidula supplements were analyzed. More than half (11/21; 52.4%) of the Acacia rigidula supplement brands contained BMPEA. The stimulant was present at quantities such that consumers following recommended maximum daily servings would consume a maximum of 93.7 mg of BMPEA per day. Consumers of Acacia rigidula supplements may be exposed to pharmacological dosages of an amphetamine isomer that lacks evidence of safety in humans. The FDA should immediately warn consumers about BMPEA and take aggressive enforcement action to eliminate BMPEA in dietary supplements. Copyright © 2015 John Wiley & Sons, Ltd.

Twitter Demographics

The data shown below were collected from the profiles of 71 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
United States 1 2%
South Africa 1 2%
Canada 1 2%
Unknown 58 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 18%
Student > Ph. D. Student 10 16%
Student > Bachelor 9 15%
Student > Master 5 8%
Professor > Associate Professor 5 8%
Other 11 18%
Unknown 11 18%
Readers by discipline Count As %
Medicine and Dentistry 11 18%
Agricultural and Biological Sciences 9 15%
Chemistry 8 13%
Pharmacology, Toxicology and Pharmaceutical Science 8 13%
Biochemistry, Genetics and Molecular Biology 4 6%
Other 12 19%
Unknown 10 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 534. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2020.
All research outputs
#21,186
of 16,084,883 outputs
Outputs from Drug Testing and Analysis
#4
of 1,011 outputs
Outputs of similar age
#323
of 228,585 outputs
Outputs of similar age from Drug Testing and Analysis
#1
of 14 outputs
Altmetric has tracked 16,084,883 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,011 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,585 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.