↓ Skip to main content

Wiley Online Library

Engineering of Nanoparticle Size via Electrohydrodynamic Jetting

Overview of attention for article published in Bioengineering & Translational Medicine, May 2016
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
twitter
3 tweeters

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
23 Mendeley
Title
Engineering of Nanoparticle Size via Electrohydrodynamic Jetting
Published in
Bioengineering & Translational Medicine, May 2016
DOI 10.1002/btm2.10010
Pubmed ID
Authors

Rahmani, Sahar, Ashraf, Sumaira, Hartmann, Raimo, Dishman, Acacia F., Zyuzin, Mikhail V., Yu, Chris K. J., Parak, Wolfgang J., Lahann, Joerg, Sahar Rahmani, Sumaira Ashraf, Raimo Hartmann, Acacia F. Dishman, Mikhail V. Zyuzin, Chris K. J. Yu, Wolfgang J. Parak, Joerg Lahann

Abstract

Engineering the physical properties of particles, especially their size, is an important parameter in the fabrication of successful carrier systems for the delivery of therapeutics. Here, various routes were explored for the fabrication of particles in the nanosize regime. It was demonstrated that the use of a charged species and/or solvent with high dielectric constant can influence the size and distribution of particles, with the charged species having a greater effect on the size of the particles and the solvent a greater effect on the distribution of the particles. In addition to the fabrication of nanoparticles, their fractionation into specific size ranges using centrifugation was also investigated. The in vitro particle uptake and intracellular transport of these nanoparticles was studied as a function of size and incubation period. The highest level of intralysosomal localization was observed for the smallest nanoparticle group (average of 174 nm), followed by the groups with increasing sizes (averages of 378 and 575 nm), most likely due to the faster endosomal uptake of smaller particles. In addition, the internalization of nanoparticle clusters and number of nanoparticles per cell increased with longer incubation periods. This work establishes a technological approach to compartmentalized nanoparticles with defined sizes. This is especially important as relatively subtle differences in size can modulate cell uptake and determine intercellular fate. Future work will need to address the role of specific targeting ligands on cellular uptake and intracellular transport of compartmentalized nanoparticles.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 35%
Student > Master 5 22%
Researcher 4 17%
Student > Doctoral Student 3 13%
Student > Postgraduate 1 4%
Other 2 9%
Readers by discipline Count As %
Chemical Engineering 4 17%
Materials Science 3 13%
Chemistry 3 13%
Engineering 3 13%
Agricultural and Biological Sciences 2 9%
Other 8 35%

Attention Score in Context

This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2016.
All research outputs
#281,230
of 8,088,896 outputs
Outputs from Bioengineering & Translational Medicine
#1
of 47 outputs
Outputs of similar age
#16,250
of 269,686 outputs
Outputs of similar age from Bioengineering & Translational Medicine
#1
of 14 outputs
Altmetric has tracked 8,088,896 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 47 research outputs from this source. They receive a mean Attention Score of 4.3. This one scored the same or higher as 46 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,686 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.