Title |
Vitiligo as an inflammatory skin disorder: a therapeutic perspective
|
---|---|
Published in |
Pigment Cell & Melanoma Research, December 2011
|
DOI | 10.1111/j.1755-148x.2011.00939.x |
Pubmed ID | |
Authors |
Alain Taïeb |
Abstract |
From a therapeutic standpoint, vitiligo is still regarded by many physicians as a simple problem of regenerative medicine, with the main aim to repopulate the depigmented skin with functional melanocytes from the margins of the lesions or from intact progenitors in hair follicles. However, recent research in vitiligo suggests that various local triggers alert the skin immune innate system and may precede adaptive immune responses targeting melanocytes. This scenario is close to that of other common skin inflammatory disorders like psoriasis and atopic, and suggests to target as a priority this clinically silent inflammatory component of he disease. This perspective highlights possible targets for intervention. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 2% |
South Africa | 1 | 2% |
Canada | 1 | 2% |
Unknown | 44 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 19% |
Student > Master | 8 | 17% |
Researcher | 7 | 15% |
Student > Postgraduate | 3 | 6% |
Student > Bachelor | 2 | 4% |
Other | 10 | 21% |
Unknown | 8 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 32% |
Agricultural and Biological Sciences | 9 | 19% |
Biochemistry, Genetics and Molecular Biology | 4 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Other | 3 | 6% |
Unknown | 12 | 26% |